Dinotefuran is a neonicotinoid insecticide developed by Mitsui Chemicals for control of insect/pests such as aphids, whiteflies, thrips, leafhoppers, leafminers, sawflies, mole cricket, white grubs, lacebugs, billbugs, beetles, mealybugs, and cockroaches on leafy vegetables, in residential and commercial buildings, and for professional turf management. It’s also used in veterinary medicine as a flea and tick preventative for dogs and as a flea preventative for cats. It is used in combination with pyriproxifen or permethrin. Its mechanism of action involves disruption of the insect's nervous system by inhibiting nicotinic acetylcholine receptors. In order to avoid harming beneficial insects such as bees, it should not be applied during bloom.